St. Luke’s Lecture 1987

10/12/1987 in Royal College of Physicians of Ireland, 6, Kildare Street, Dublin 2

Dr. Carmel Mothersill

The Saint Luke’s Lecture was held on 10th December 1987 in the College of Physicians when Dr. Carmel Mothersill presented her lecture on Radiation, Cancer and Cell Culture Models. The President of the Academy presided and with him was Mr. Reginald Redmond, Chairman of Saint Luke’s Hospital Board.

Dr. Mothersill began with the introduction of the two main themes — radiation as a cause of cancer and radiation as a therapy for cancer. She then went on to show how and why cell culture had contributed to the investigation of these two areas. Various types of model systems were introduced and their relative merits discussed. These included the use of established cell lines to gain information on cell killing by radiation and the use of the relatively simple C3H 10T 89 system for the study of transformation (that is in vitro carcinogenesis). Dr. Mothersill then discussed the importance of human cell culture work and mentioned possible reasons for its sparcity.

Irish Journal of Medical Science January 1988, Volume 157, Issue 1, pp 32-34

This being the twelfth St. Luke’s Lecture since its beginnings in 1975.